Pharmaceutical Technology PYQs – Set 97

By Atul Sahu • Pharmaceutical Technology, Subject Wise PYQs

Pharmaceutical Technology PYQs – Set 97

Subject : Pharmaceutical Technology

1921. The required amount of adjusting substance to make a hypotonic solution isotonic is given by (W = adjusting substance, a = freezing point depression of unadjusted solution, b = freezing point depression of water):

Pharmaceutical Technology • Preformulation • GPAT 2023

A. W = (a − 0.52)/b B. W = (0.52 − a)/b C. W = (0.52 − b)/a D. W = (b − 0.52)/a

1922. Clear, sweetened hydroalcoholic solutions intended for oral use, usually flavored to enhance palatability, are called:

Pharmaceutical Technology • Preformulation • GPAT 2023

A. Aromatic waters B. Elixirs C. Syrups D. Tinctures

1923. What is the percentage of alcohol in a mixture obtained by mixing 5 L of 25%, 3 L of 40%, and 2 L of 15% alcohol?

Pharmaceutical Technology • Preformulation • GPAT 2023

A. 27.5% v/v B. 30.5% v/v C. 25.5% v/v D. 26.5% v/v

1924. A 2.0% saline solution is considered

Pharmaceutical Technology • Preformulation • GPAT 2023

A. Hypotonic B. Hypertonic C. Isotonic D. Iso-osmotic

1925. Noye-Whitney's equation predicts that

Pharmaceutical Technology • Preformulation • GPAT 2023

A. an increase in dissolution rate occurs with reduced particle size due to increased surface area B. a relationship between diffusion coefficient and molecular size C. the influence of electrolyte concentration on dissolution rate D. an equilibrium between surfactant molecules at interfaces

1926. Which equation explains the increase in solubility with decreasing particle size?

Pharmaceutical Technology • Preformulation • GPAT 2023

A. Log(S0/S)=2γMr/2.303RTρ B. Log(S/S0)=2γMr/2.303RTρ C. Log(S0/S)=2γMr/2.303 RTρr D. Log(S/S0)=2γM/2.303 RTρr

1927. Match List I with List II for dissolution apparatus: A. Type 1, B. Type 5, C. USP App 6, D : USP App 7; and List II: I. Reciprocating holder, II. Paddled overdisk, III. Basket type, IV. Cylinder apparatus.

Pharmaceutical Technology • Preformulation • GPAT 2023

A. (A)-(III); (B)-(II); (C)-(IV); (D)-(I) B. (A)-(IV); (B)-(I); (C)-(II); (D)-(III) C. (A)-(II); (B)-(III); (C)-(I); (D)-(II) D. (A)-(I); (B)-(II); (C)-(III); (D)-(IV)

1928. A clear, sweetened hydroalcoholic liquid containing medicament is known as

Pharmaceutical Technology • Preformulation • GPAT 2023

A. Elixir B. Syrup C. Tincture D. Decoction

1929. Which of the following is not a method for solubility enhancement:

Pharmaceutical Technology • Preformulation • GPAT 2023

A. Crystallization B. Co-solvency C. Hydrotropy D. Salt formation

1930. An elixir contains 47% v/v alcohol, what is the proof spirit according to USP:

Pharmaceutical Technology • Preformulation • GPAT 2023

A. 0.82 B. 0.7 C. 0.63 D. 0.91

1931. Hot stage microscopy is an important tool in preformulation studies for the study of

Pharmaceutical Technology • Preformulation (Hot‑Stage Microscopy) • GPAT 2023

A. Pseudopolymorphism B. Particle size measurement C. Microbial contamination D. Compaction behaviour

1932. Which of the following is not a thermoplastic resin

Pharmaceutical Technology • Preformulation (Resin Classification) • GPAT 2023

A. Phenolic plastic resin B. Polystyrene C. Polyethylene D. Polypropylene

1933. Human Serum Albumin has a molecular weight of

Pharmaceutical Technology • Protein therapeutics • GPAT 2023

A. 34000 B. 65000 C. 44000 D. 59000

1934. Pyrogens in containers are destroyed by heating at:

Pharmaceutical Technology • Pyrogen destruction • GPAT 2023

A. 121°C for 15 mins B. 121°C for 30 mins C. 210°C for 4 h D. 210°C for 1 h

1935. Containers may be rendered free from pyrogens by adequate cleaning and by:

Pharmaceutical Technology • Pyrogen removal • GPAT 2023

A. Autoclaving at 121°C for 15 minutes B. Heating at 210°C for 3-4 hours C. Autoclaving at 121°C for 1 hour D. Heating at 100°C for 3-4 hours

1936. Which of the following is not added to chewing tablets?

Pharmaceutical Technology • Receptor Pharmacology • GPAT 2023

A. Gildant B. Disintegrant C. Lubricant D. Antiadhesive

1937. The bloom strength is directly proportional to:

Pharmaceutical Technology • Rheology + Kinetics & Drug Stability • GPAT 2023

A. Density B. Viscosity C. Measure of the strength and stiffness of the gelatin D. Molecular weight

1938. Which one of the following viscometers can be used for characterizing non-Newtonian system ?

Pharmaceutical Technology • Rheology measurement • GPAT 2023

A. Falling sphere viscometer B. Cup and Bob viscometer C. Capillary viscometer D. Hoeppler viscometer

1939. The fraction of an administered dose (e.g., of an ester or salt) of active drug is termed as

Pharmaceutical Technology • Salt and activity factors • GPAT 2023

A. Activity factor B. Formulation factor C. Intrinsic factor D. Salt factor

1940. Identify the false statement about magmas:

Pharmaceutical Technology • Semisolid + Suppository + Aerosol • GPAT 2023

A. The addition of suspending agents to magmas is always necessary B. Magmas differ from gels in that their suspended particles are larger C. Magmas are two-phase systems D. Magmas are essentially gels

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