Pharmaceutical Technology PYQs – Set 96

By Atul Sahu • Pharmaceutical Technology, Subject Wise PYQs

Pharmaceutical Technology PYQs – Set 96

Subject : Pharmaceutical Technology

1901. For bitter drugs in paediatric formulations, excellent flavouring agent will be.

Pharmaceutical Technology • Pediatric flavoring agents • GPAT 2019

A. Raspberry syrup B. Orange syrup C. Lemon syrup D. Black current syrup

1902. Dimethyl sulfoxide acts as penetration enhancer for topical formulations by

Pharmaceutical Technology • Penetration enhancers • GPAT 2019

A. Increasing solubility B. Denaturing proteins C. Increasing transepidermal loss D. Altering solvent nature of membrane

1903. Dividing lubricant by passing it through a 60–100 mesh cloth is termed?

Pharmaceutical Technology • Powder Technology • GPAT 2019

A. Bolting B. Mixing C. Tumbling D. Grinding

1904. Identify the structure of barbituric aciD :

Pharmaceutical Technology • Preformulation • GPAT 2019

A. (Option A) B. (Option B) C. (Option C) D. (Option D)

1905. How does the wetting agent act in a suspension?

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Increase contact angle between substance and solvent B. Reduce contact angle between substance and solvent C. No change in contact angle D. None of the above

1906. According to USP, alcohol contains

Pharmaceutical Technology • Preformulation • GPAT 2019

A. 94.9–96% Ethanol B. 94.9–96% Methanol C. 50% Ethanol D. 50% Methanol

1907. Amount of dextrose in large volume infusion fluids is typically

Pharmaceutical Technology • Preformulation • GPAT 2019

A. 5% w/v B. 10% w/v C. 25% w/v D. 50% w/v

1908. ‘Sparging’ is the process where

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Silanol groups react with trimethylsilyl groups B. An inert gas is bubbled through the solvent to remove dissolved gases C. Solvents are mixed together in a fixed ratio D. A column is washed with solvents from nonpolar to polar

1909. ‘Sparging’ is the process where

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Silanol groups react with trimethylsilyl groups B. An inert gas is bubbled through the solvent to remove dissolved gases C. Solvents are mixed in a fixed ratio D. A column is washed with solvents from nonpolar to polar

1910. Which percentage of dextrose is isotonic with the blood plasma?

Pharmaceutical Technology • Preformulation • GPAT 2019

A. 0.05 B. 0.1 C. 0.15 D. 0.2

1911. What is the significance of the term “overfill”?

Pharmaceutical Technology • Preformulation • GPAT 2019

A. It is similar to overage B. It is the excess volume filled in containers (e.g., vials, ampoules) to avoid loss by degradation C. It is the excess filling of containers to avoid loss during packaging D. It is a violation of packaging regulation as per GMP

1912. What is the half-life of Tc-99m?

Pharmaceutical Technology • Preformulation • GPAT 2019

A. 66 years B. 66 hours C. 6 hours D. 60 minutes

1913. Which one of the following techniques is used to determine glass transition temperature?

Pharmaceutical Technology • Preformulation • GPAT 2019

A. X-ray diffractometry B. Raman spectroscopy C. Differential scanning calorimetry D. Atomic force microscopy

1914. Foaming during liquid filling can be reduced by all of the following except

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Increase in speed of the filling line B. Minimized product turbulence C. Closed system filling D. Use of a defoaming device

1915. The agent used to prevent dental caries is:-

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Sodium fluoride B. Strontium chloride C. Zinc chloride D. Dicalcium phosphate

1916. As per USP, the test limit for treated soda lime glass with a container size of 200 mL is:-

Pharmaceutical Technology • Preformulation • GPAT 2019

A. 0.70 mL of 0.02N acid B. 1.0 mL of 0.2N acid C. 0.20 mL of 0.02N acid D. 0.70 mL of 0.2N acid

1917. In preformulation study polymorphs can be detected by

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Counter-current chromatography B. Retractometry C. High performance liquid chromatography D. Differential scanning

1918. A change in which excipient affects tablet dissolution?

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Starch B. Magnesium stearate C. Microcrystalline cellulose D. Lactose

1919. Which complex is NOT an inclusion compound?

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Channel-Lattice B. Quinhydrone C. Layer Type D. Clathrates

1920. Identify the false statement about dyes.

Pharmaceutical Technology • Preformulation • GPAT 2019

A. Reducing agents cause dye fading B. Anionic dyes are stable in acid C. Basic dyes are not sensitive to alkali D. Cationic dyes may precipitate with soaps

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