NIPER PYQs – Set 93

Year: 2020

1841. Which of the following drugs works as a proteosome inhibitor

Pharmacology & Toxicology • Anticancer Agents

A. Nilotinib B. Infliximab C. Bortezomib D. Filgrastim

1842. All of the following are typical cholinergic effects EXCEPT

Pharmacology & Toxicology • Cholinergic Effects

A. a decrease in heart rate and contraction of bronchial muscle B. a decrease in conduction velocity through the AV node C. an increase in sweat secretion D. an increase in pupillary diameter

1843. Agarose is a polysaccharide, composed of

Pharmaceutical Biotechnology • Polysaccharides

A. D-galactose and agarobiose B. D-glucuronic acid and sulfated D-glucuronic acid C. D-glucuronic acid and glucosamine D. D-galactose and 3,6-anhydro-L-galactopyranose

1844. Which of the following forces is dictated by entropic effects

Pharmaceutical Analysis • Physical Chemistry

A. atom-atom repulsion based on the Pauli Exclusion principle B. electrostatic interactions C. hydrophobic interactions D. charge-transfer interactions

1845. Which of the following functional groups is a classical isostere for -CH=?

Organic Chemistry & Bulk Drugs • Isosterism

A. 0 B. -NH- C. -N= D. COOH

1846. As much as 70 per cent of all the APIs needed by India to manufacture drugs come from

Practice of Pharmacy • Pharmaceutical Industry

A. China B. India C. Taiwan D. Belgium

1847. Alogliptin, saxagliptin, vildagliptin have a structural feature common that is responsible for reaction with DPP-4. What is that

Pharmacology & Toxicology • DPP-4 Inhibitors

A. Nitrilo group B. β-aminoacid group C. Adamantane ring D. Pyrollidine

1848. The approximate δ value of methyl proton in 1H-NMR is

Pharmaceutical Analysis • NMR Spectroscopy

A. 1.3 B. 1.5 C. 0.9 D. 2.5

1849. 100 proof ethanol means it is

Organic Chemistry & Bulk Drugs • Chemical Properties

A. 1 B. 0.75 C. 0.6 D. 0.5

1850. Select the drug indicated for extended drug resistance tuberculosis (XDR TB)

Pharmacology & Toxicology • Antitubercular Agents

A. Linezolid B. Moxifloxacin C. Tyrocidin D. Azithromycin

1851. Which of the following quantities is not changed at different magnetic field strength

Pharmaceutical Analysis • NMR Spectroscopy

A. Chemical shift (in Hz) B. Nuclear spin population in an energy state C. J-coupling constant D. Energy difference between two energy states of nuclei with nonzero spin quantum number

1852. Choose the WRONG statement about mass spectrometry with ESI

Pharmaceutical Analysis • Mass Spectrometry

A. It is very unlikely for adducts to occur during ESI. B. ESI can be used for thermally labile analytes. C. Adjusting the pH might enhance the generation of ions. D. It has easy compatibility with LC

1853. Which are the host cell membrane receptors that the outer coat protein gp-120 of HIV binds to

Pharmacology & Toxicology • Virology

A. CD4 and CCR5 B. pepsin and adenylyl cyclase C. IP3 and cytochrome-c D. bicoid and nanos

1854. In LC-MS instrument, interface is applied between

Pharmaceutical Analysis • Mass Spectrometry

A. LC column and mass separator B. Injection and ion source C. LC column and ion source D. LC column and detector

1855. Microwave spectroscopy is generally used to detect

Pharmaceutical Analysis • Spectroscopy

A. Functional groups B. Double bonds C. Isotopes D. Unpaired electrons

1856. Which of the following is not true

Practice of Pharmacy • General Knowledge

A. Magnets (200 MHz-900 MHz) are made of superconducting wires B. Room temperature shims are in a liquid nitrogen vessel C. Liquid helium and liquid nitrogen are needed to maintain the magnetic field D. The magnet solenoid is in a liquid helium vessel

1857. The purpose of shimming is to

Pharmaceutical Analysis • Instrumental Analysis

A. Stabilize the static magnetic field B. Obtain homogeneity of the static magnetic field C. Find the lock frequency D. Obtain homogeneity of the B1 field

1858. Tyndall effect is shown by

Pharmaceutical Analysis • Colloids

A. particles in colloidal solution B. particles in very fine suspension C. Aerosols D. All of the above

1859. Who is the founder of Lupin

Practice of Pharmacy • Pharmaceutical History

A. Desh Bandhu Gupta B. Khwaja Abdul Hamied C. Dilip Shanghvi D. Habil Khorakiwala

1860. Neutropenia is adverse effects of all of the following EXCEPT

Pharmacology & Toxicology • Adverse Effects

A. Rituximab & Ganciclovir B. Phenytoin & Clarithromycin C. Propyl thiouracil & Carbamazepine D. Clozapine & Colchicine

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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NIPER PYQs – Set 93

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