NIPER PYQs – Set 25
Year: 2013
481. Using the FDA bioequivalence rule, how much variation could a generic drug potentially have from an innovator and still be considered equivalent?
Regulatory Affairs & IPR • FDA Bioequivalence Variation
482. Which of the following descriptions is CORRECT about gyrase?
Pharmaceutical Biotechnology • Gyrase Function
483. In March 2012, India granted its first compulsory license for anti-cancer drug by Indian Patent office to:
Regulatory Affairs & IPR • Compulsory License
484. Why is penicillin G sensitive to acid and enzyme-catalyzed hydrolysis?
Medicinal Chemistry • Penicillin Stability
485. Which of the following drugs interacts selectively with a specific subtype of the benzodiazepine receptor and is used to treat insomnia?
Pharmacology & Toxicology • Selective Benzodiazepine Receptor Agonist
486. Tropane system is fusion of:
Organic Chemistry & Bulk Drugs • Tropane Structure
487. DNA in mammal cells is also present in:
Pharmaceutical Biotechnology • Mitochondrial DNA
488. The composition of Silica gel G is:
Pharmaceutics & Formulation • Silica Gel Composition
489. Twenty different amino acids found in proteins are normally coded by:
Pharmaceutical Biotechnology • Genetic Code
490. DPCO is issued under which act?
Regulatory Affairs & IPR • DPCO Act
491. Which one of the following is second generation H1-antihistamine?
Pharmacology & Toxicology • Second Generation H1-Antihistamine
492. The Chairman of the Investigational New Drug (IND) Committee in India is:
Regulatory Affairs & IPR • IND Committee Leadership
493. Which of the following is not used as enteric coating material?
Pharmaceutics & Formulation • Enteric Coating Materials
494. Which is the only genetically modified crop/food plant approved in India
General Knowledge • Genetically Modified Crops in India
495. The IPR in India is implemented with:
Regulatory Affairs & IPR • IPR Implementation in India
496. The Freundlich adsorption isotherm can be used to model:
Pharmaceutical Analysis • Adsorption Isotherms (Freundlich)
497. For dissolution testing of implants, which apparatus is used?
Pharmaceutics & Formulation • Implant Dissolution Apparatus
498. During hemoglobin recycling in the spleen, heme is initially converted into:
Pharmaceutical Biotechnology • Hemoglobin Metabolism
499. Identify the virus used for gene delivery in gene therapy.
Pharmaceutical Biotechnology • Gene Therapy Vectors
500. The reductions take place at which electrode?
Pharmaceutical Analysis • Electrochemistry – Reduction Electrode
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