Medicinal Chemistry PYQs – Set 53
Subject : Medicinal Chemistry
1041. Which of the following is a Lewis base?
Medicinal Chemistry • • NIPER 2015
1042. In drug development, racemic switch is introduced for the synthesis of:
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1043. The ring system in lidocaine is:
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1044. Which of the following species is the most nucleophilic?
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1045. Which of the following bonds requires more energy to stretch?
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1046. Supramolecular chemistry is:
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1047. OsO₄ is used for the dihydroxylation of alkenes. The stereochemistry of the two hydroxyl groups is:
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1048. Esters and amides are most easily made by nucleophilic acyl substitution reactions on:
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1049. Carbocation stability increases in the order 3° > 2° > 1° > -CH₃. What is the reason?
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1050. Which of the following is the closest derivative of dopamine?
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1051. When 3-iodo-3-ethylpentane is treated with sodium methoxide in methanol, the major organic product is an ___ that is generated through an ___ mechanism:
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1052. Allenes exhibit optical isomerism due to the presence of:
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1053. Which of the following would react faster with N-bromosuccinimide?
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1054. The nucleophilicity of different halide ions in polar aprotic solvent is:
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1055. α,β-unsaturated carbonyl compounds undergo a ring closure reaction with conjugated dienes. The reaction is called as:
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1056. Which heterocyclic ring system is present in hydralazine:
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1057. Conversion of one of the conformations to another involves:
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1058. When 1-pentanol is heated with HCl/ZnCl₂, 1-chloropentane is the major organic product. The reaction proceeds through an ____ mechanism, and ____ is produced as a by-product:
Medicinal Chemistry • • NIPER 2015
1059. Only one of the following compounds is aromatic. Which one?
Medicinal Chemistry • • NIPER 2015
1060. Which of the following are 'concerted' reactions?
Medicinal Chemistry • • NIPER 2015
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