GPAT PYQs – Set 39

Year: 2015

764. ‘Sparging’ is the process where

Pharmaceutical Technology • Preformulation

A. Silanol groups react with trimethylsilyl groups B. An inert gas is bubbled through the solvent to remove dissolved gases C. Solvents are mixed together in a fixed ratio D. A column is washed with solvents from nonpolar to polar

765. Morphine does not cause

Pharmacology • Drugs Acting on Autonomic Nervous System

A. Constriction of the pupil B. CNS depression C. Respiratory depression D. Diarrhea

766. Which of the following is not recommended in patients with renal insufficiency or cardiac dysfunction?

Pharmacology • Respiratory Pharmacology + GIT Pharmacology

A. Aloe B. Bisacodyl C. Isabgol D. Magnesium hydroxide

767. Higuchi model is applicable to a drug that is

Biopharmaceutics • Drug Dissolution and Release Kinetics

A. Dissolved in the formulation B. Dispersed in the formulation C. Chemically bound to the carrier in the formulation D. Osmotically controlled in the formulation

768. Which of the following is correct about parenteral nutrition?

Pharmaceutical Technology • Parenteral + Sterilization

A. Parenteral nutrition solutions are hypertonic and IV fluids are isotonic B. Both are isotonic solutions C. Parenteral nutrition solutions are hypertonic and IV fluids are hypertonic D. Parenteral nutrition solutions are isotonic and IV fluids are hypertonic

769. Cyclic AMP (cAMP) is an important second messenger. Which enzyme catalyzes its generation after a receptor-ligand interaction?

Biochemistry • Enzymes and Coenzymes

A. Protein kinase A B. cAMP phosphodiesterase C. Guanylyl cyclase D. Adenylate cyclase

770. Which of the following is not included in the immunization programme as per WHO recommendations for all children?

Microbiology • Immunology and Vaccines

A. BCG B. Oral polio C. Measles D. Typhoid

771. In mammals, the major fat in adipose tissue is

Biochemistry • Lipid and Protein Metabolism

A. Triglyceride B. Cholesterol C. Sphingophospholipids D. Phospholipids

772. What is the nuclear magnetic resonance frequency of ¹H in a 7.05 Tesla magnetic field?

Pharmaceutical Analysis • Spectroscopy

A. 300.0 MHz B. 200.0 MHz C. 60.0 MHz D. 100 MHz

758. Consider the reaction: A + B → C. What is the unit of the thermodynamic equilibrium constant for this reaction?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. mol/L B. L/mol C. mol²/L² D. Dimensionless

774. Elementary Osmotic Pump, L-OROS, Sandwich Osmotic Pump Tablet, and Controlled Porosity Osmotic Pump Tablet: which system does not have an orifice to release the drug?

Pharmaceutical Technology • Controlled‑Release Technologies

A. Elementary Osmotic Pump B. L-OROS C. Sandwich Osmotic Pump Tablet D. Controlled Porosity Osmotic Pump Tablet

775. Sanguinarine belongs to which subgroup?

Pharmacognosy • Alkaloids

A. Morphinans B. Benzyl isoquinolines C. Phthalide isoquinolines D. Benzophenanthrenes

776. The IUPAC name, 4-Amino-N(5,6-dimethoxy-4-pyrimidinyl)benzene sulfonamide belongs to which generic drug?

Medicinal Chemistry • Heterocyclic Chemistry

A. Sulfadimidine B. Sulfadoxine C. Sulfalene D. Sufamerazine

777. Tamoxifen is a nonsteroidal drug acting at steroid receptors. It produces which effect?

Pharmacology • Drugs Acting on Endocrine System

A. Androgenic B. Antiestrogenic C. Antiprogestogenic D. Estrogenic

778. Which enzyme is used by HIV to form DNA in the host cell?

Biochemistry • Molecular Biology

A. Restriction endonuclease B. DNA-directed polymerase only C. Reverse transcriptase only D. Both (b) and (c)

779. ‘Sparging’ is the process where

Pharmaceutical Technology • Preformulation

A. Silanol groups react with trimethylsilyl groups B. An inert gas is bubbled through the solvent to remove dissolved gases C. Solvents are mixed in a fixed ratio D. A column is washed with solvents from nonpolar to polar

780. Morphine does not cause

Pharmacology • Drugs Acting on Autonomic Nervous System

A. Pupillary constriction B. CNS depression C. Respiratory depression D. Diarrhea

781. Which of the following is not recommended in patients with renal insufficiency or cardiac dysfunction?

Pharmacology • Respiratory Pharmacology + GIT Pharmacology

A. Aloe B. Bisacodyl C. Isabgol D. Magnesium hydroxide

782. Higuchi model is applicable to a drug that is

Pharmaceutical Technology • Controlled‑Release Technologies

A. Dissolved in the formulation B. Dispersed in the formulation C. Chemically bound to a carrier D. Osmotically controlled in the formulation

783. Which of the following is not a component of an evaporator?

Pharmaceutical Engineering • Evaporation & Drying

A. Heat exchanger B. Vacuum separator C. Condenser D. Cyclone separator

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The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

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GPAT PYQs – Set 39

GPAT PYQs – Set 39

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GPAT PYQs – Set 39

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