GPAT PYQs – Set 18

By Atul Sahu • GPAT PYQs

GPAT PYQs – Set 18

Year: 2023

341. Which type of hepatitis can lead to fulminant hepatitis with high third trimester mortality in pregnant women?

Microbiology • Complete Subject

A. Hepatitis A B. Hepatitis B C. Hepatitis C D. Hepatitis E

342. Phocomelia is caused by

Pharmacology • General Pharmacology

A. Glibenclamide B. Indapamide C. Xipamide D. Thalidomide

343. Valproate and Carbamazepine can be used as first-line drugs for the management of which type of seizure?

Pharmacology • Drugs Acting on Central Nervous System

A. Both partial and tonic-clonic seizures B. Both tonic-clonic seizures and status epilepticus C. Only febrile seizures D. Both febrile seizures and status epilepticus

344. Which phase of the cell cycle is the shortest?

Human Anatomy and Physiology • Complete Subject

A. G1 B. S C. M D. G2

345. The primary purpose of a spiral scrapper in a Swenson-Walker crystalliser is

Pharmaceutical Engineering • Crystallization and Separation

A. Agitation of the sample (solution) B. Conveying the crystals C. Preventing accumulation of crystals on the cooling surface D. Providing desired temperature to the solution

346. Match List I with List II for photopharmaceuticals: A. Penicillin, B. Pruteen, C. Streptomycin, D : Amino acids; and List II: I. Single cell protein, II. Ion exchange chromatography for recovery, III. Primary metabolite, IV. Phenyl acetic acid as precursor.

Pharmacognosy • Introduction to Pharmacognosy

A. (A)-(II); (B)-(I); (C)-(IV); (D)-(III) B. (A)-(IV); (B)-(I); (C)-(II); (D)-(III) C. (A)-(III); (B)-(II); (C)-(I); (D)-(IV) D. (A)-(II); (B)-(III); (C)-(IV); (D)-(I)

347. Who is the primary source of information for doctors' prescribing behavior?

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. Competitor B. Wholesaler C. Fellow doctor D. Retailer

348. Schedule 'O' governs standards for which aspect of drug manufacturing?

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. Disinfectant fluids B. List of equipment to run a pharmacy C. Shelf-life (expiry) of drugs D. Manufacturing and analytical records

349. Fluid flow through a filter medium occurs due to

Pharmaceutical Engineering • Filtration and Flow

A. Pressure difference across the filter B. Temperature difference across the filter C. Volume difference across the filter D. Potential difference across the filter

350. Match the photopharmaceutical with its plant source: A. Cardinolides, B. Rutin, C. Ajamalicine, D : Codeine; and Plant species: I. Ruta graveolens, II. Catharanthus roseus, III. Papaver somnifera, IV. Digitalis lanata.

Pharmacognosy • Alkaloids

A. (A)-(IV); (B)-(I); (C)-(II); (D)-(III) B. (A)-(I); (B)-(III); (C)-(II); (D)-(IV) C. (A)-(III); (B)-(I); (C)-(III); (D)-(IV) D. (A)-(II); (B)-(IV); (C)-(I); (D)-(III)

351. Specific requirements for the manufacture of sterile products and parenteral preparations are detailed in which part of Schedule-M?

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. PART-IV B. PART-IB C. PART-IC D. PART-ID

352. Fight or flight responses are mediated by

Pharmacology • Drugs Acting on Autonomic Nervous System

A. Parasympathetic division B. Sympathetic division C. Serotonergic system D. Histaminergic system

353. Which autosomal dominant syndrome is characterized by mild unconjugated hyperbilirubinemia?

Human Anatomy and Physiology • Complete Subject

A. Gilbert's syndrome B. Crigler-Najjar syndrome Type-I C. Dubin-Johnson syndrome D. Rotor syndrome

354. Match the acetylcholine receptor subtypes with their predominant locations:

Pharmacology • Drugs Acting on Autonomic Nervous System

A. M1 confined to brain; M2 neural; M3 cardiac; M4 glandular B. M1 neural; M2 confined to brain; M3 cardiac; M4 glandular C. M1 neural; M2 cardiac; M3 glandular; M4 confined to brain D. M1 glandular; M2 neural; M3 brain; M4 cardiac

355. Which urinary protein marker is detectable within three hours of acute ischemic kidney injury?

Biochemistry • Protein Metabolism

A. N-acetyl-β-D-glucosaminidase B. Glutathione-S-transferase C. Neutrophil gelatinase associated lipocalin D. γ-glutamyl transpeptidase

356. Which gene plays a crucial role in graft rejection?

Human Anatomy and Physiology • Complete Subject

A. Highly polymorphic HLA genes B. APP genes C. hMSH2 gene D. FMR1 gene

357. Most common type of megaloblastic anemia due to vitamin B12 malabsorption is

Human Anatomy and Physiology • Complete Subject

A. Iron deficiency anemia B. Sideroblastic anemia C. Pernicious anemia D. Aplastic anemia

358. Which of the following is not an ACE inhibitor?

Pharmacology • Drugs Acting on Cardiovascular System

A. Captopril B. Tarandopril C. Verapamil D. Lisinopril

359. Which combination of antiviral drugs is correctly paired?

Pharmacology • Antimicrobial Agents

A. NRTIs - Ritonavir B. Protease inhibitors - Indinavir C. Integrase inhibitors - Saquinavir D. NNRTIs - Tenofovir

360. Which drug is used in the treatment of gout by inhibiting xanthine oxidase?

Pharmacology • autocoids

A. Probenecid B. Allopurinol C. Colchicine D. Indomethacin

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GPAT PYQs – Set 18

GPAT PYQs – Set 18

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GPAT PYQs – Set 18

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