GPAT PYQs – Set 11
Year: 2023
201. Trastuzumab is classified as which type of therapeutic agent?
Pharmacology • Antimicrobial Agents
202. When is a New Drug Application (NDA) typically submitted?
Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940
203. Identify the drug that is not recommended as a first‑line treatment for partial seizures.
Pharmacology • Drugs Acting on Central Nervous System
204. Which hyperlipidemic drug acts via a G-protein–coupled receptor mechanism?
Pharmacology • Diuretics + Blood
205. Which of the following is not classified as a TNF‑α inhibitor?
Pharmacology • Diuretics + Blood
206. Which drug can produce mydriasis without causing cycloplegia?
Pharmacology • Drugs Acting on Autonomic Nervous System
207. Which of the following best defines an orphan drug?
Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940
208. What is the typical normal range of HbA1c in non‑diabetic individuals?
Human Anatomy and Physiology • Complete Subject
209. A 70‑kg woman receives a 1000‑mg IV bolus of a drug, resulting in a plasma concentration of 50 mg/L. What is the volume of distribution?
Biopharmaceutics • ADME
210. A hypertensive patient on drug ‘Y’ loses antihypertensive control when a tricyclic antidepressant is addeD : Which drug is most likely ‘Y’?
Pharmacology • Drugs Acting on Cardiovascular System
211. Which of the following is not an example of an mTOR inhibitor?
Pharmacology • Antimicrobial Agents
212. Alzheimer's disease is mainly associated with neurodegeneration in which region of the brain?
Pharmacology • Drugs Acting on Autonomic Nervous System
213. Which drug has been found to act as a male contraceptive without affecting libido or potency?
Pharmacology • Drugs Acting on Endocrine System
214. Select the most appropriate statement regarding NSAID-induced peptic ulcer disease.
Pharmacology • autocoids
215. The lateral geniculate nucleus is primarily associated with which sensory modality?
Human Anatomy and Physiology • Complete Subject
216. Which oral oligosaccharide hypoglycemic agent is administered at the start of a meal?
Pharmacology • Drugs Acting on Endocrine System
217. Which functional group is crucial for the antimalarial activity of artemisinin?
Pharmacology • Antimicrobial Agents
218. Select the drug that exhibits dual alpha and beta adrenergic receptor agonist activity.
Pharmacology • Drugs Acting on Autonomic Nervous System
219. In universal indicators, a pH of 7 is typically indicated by which color?
Physical and Inorganic Chemistry • Acids, Bases, and Buffers
220. Which statement regarding Hückel’s rule is false?
Organic Chemistry • General Organic Chemistry
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