Pharmacology PYQs – Set 124

By Atul Sahu • Pharmacology, Subject Wise PYQs

Pharmacology PYQs – Set 124

Subject : Pharmacology

2461. The following ACE inhibitor used in treating cardiovascular disorder is synthesized from the natural amino acids L-alanine and L-proline :

Pharmacology • ACE inhibitor synthesis • GPAT 2019

A. Ramipril B. Enalapril C. Insmopril D. Captopril

2462. Of the following antibiotics, which one is acceptable for treating penicillin-resistant S. pneumoniae otitis media?

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Azithromycin B. Clarithromycin C. Cefuroxime D. Cefaclor

2463. Which of the following drugs is NOT used in the treatment of H. pylori infection?

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Ampicillin B. Clarithromycin C. Mosapride D. Bismuth subgallate

2464. Chemokine co-receptor 5 (CCR5) inhibitor is:

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Enfuvirtide B. Maraviroc C. Raltegravir D. Atazanavir

2465. Match the compounds in Group I with inhibitory activities in Group II: (P) Vancomycin, (Q) Rifampin, (R) Puromycin, (S) Ciprofloxacin versus (1) Folate metabolism, (2) DNA synthesis, (3) Protein synthesis, (4) RNA synthesis, (5) Cell wall synthesis.

Pharmacology • Antimicrobial Agents • GPAT 2019

A. P-5, Q-4, R-3, S-2 B. P-4, Q-3, R-1, 5-2 C. P-4, Q-1, R-3, S-2 D. P-5, Q-3, R-2, S-4

2466. Mechanism of action of Ketoconazole is primarily through:

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Inhibition of ergosterol synthesis B. Inhibition of DNA gyrase C. Inhibition of dihydropteroate synthetase D. Induction of translation misreading

2467. Drug of choice to treat H1N1 influenza is:

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Adefovir B. Cidofovir C. Oseltamivir D. Tenofovir

2468. Match the following drugs with their mode of action: (P) Methotrexate, (Q) Cyclophosphamide, (R) Vincristine, (S) Dactinomycin with their respective mechanisms.

Pharmacology • Antimicrobial Agents • GPAT 2019

A. P-4, Q-3, R-1, S-? B. P-2, Q-4, R-1, S-3 C. P-3, Q-1, R-4, S-2 D. P-2, Q-3, R-1, S-4

2469. What is the 6-methyl derivative of erythromycin?

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Azithromycin B. Roxithromycin C. Clarithromycin D. Clindamycin

2470. A series of β-acylureido penicillins like azlocillin, mezlocillin, and piperacillin are superior because of

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Reduced acid hydrolysis B. Increased β-lactamase resistance C. Improved penetration through the cell envelope D. Slow rate of metabolism

2471. Which anthelmintic has immunosuppressant activity?

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Piperazine B. Levamisole C. Ivermectin D. Niclosamide

2472. Oseltamivir is an antiviral drug. It produces its action by inhibiting which enzyme?

Pharmacology • Antimicrobial Agents • GPAT 2019

A. DNA polymerase B. Neuraminidase C. Praziquantel D. Ivermectin

2473. Match the antimalarial drugs with their modes of action: 1. Artemisinin, 2. Pyremethamine, 3. Quinine, 4. Atovaquone/Proguanil

Pharmacology • Antimicrobial Agents • GPAT 2019

A. (a) 1-P, 2-S, 3-Q, 4-R B. (b) 1-Q, 2-5, 3-P, 4-R C. (c) 1-S, 2-R, 3-Q, 4-P D. (d) 1-R, 2-S, 3-Q, 4-P

2474. Methyl ether of erythromycin is

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Clarithromycin B. Dirithromycin C. Azithromycin D. Mithramycin

2475. An antibiotic that resembles the 3’ end of a charged tRNA molecule is

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Streptomycin B. Vincamycin C. Puromycin D. Tetracycline

2476. The most accepted mechanism for developing bacterial resistance to sulphonamides is

Pharmacology • Antimicrobial Agents • GPAT 2019

A. An alternative metabolic pathway for synthesis of essential components B. An increasing capacity to metabolize the drug C. Increased antagonism of the drug D. An alteration in the enzyme that utilizes PABA

2477. Which of the following drugs is associated with extreme photosensitivity

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Niacin B. Digitalis C. Tetracycline D. Fluoroquinolones

2478. Clavulanic acid

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Inactivates bacterial β‑lactamase B. Protein inhibitor of peptidoglycan synthesis C. Specific for gram‑negative bacteria D. Inhibitor of 50S ribosomal subunit

2479. Neuropathy is an adverse effect of

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Isoniazid B. Ethambutol C. Pyrazinamide D. Dapsone

2480. Which functional group is crucial for the antimalarial activity of artemisinin?

Pharmacology • Antimicrobial Agents • GPAT 2019

A. Aldehydic functional group B. Ethylene bridge C. Ketonic functional group D. Peroxide bridge

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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