Answer: B. Pa.sec

Explanation: Viscosity is measured in pascal-seconds (Pa·s), which quantifies a fluid’s resistance to flow. It is an SI unit that reflects the internal friction within the fluid.

Answer: D. 1-Q, 2-P, 3-S, 4-R

Explanation: According to the answer key, the correct matching of medicinal gases to cylinder shoulder colors is: CO₂ with Q (red shoulder), Hydrogen with P (green shoulder), Helium with S (white shoulder), and Oxygen with R (grey shoulder).

Answer: A. q = 0

Explanation: When a liquid completely wets a solid surface, the contact angle (q) approaches 0°. This indicates perfect wetting where the liquid spreads uniformly over the surface.

Answer: D. HPMC

Explanation: Hydroxypropyl methylcellulose (HPMC) is a hydrophilic polymer that swells in aqueous media and is widely used as a release retardant in controlled-release drug formulations.

Answer: B. Flow-through cell

Explanation: Implants are often tested using a flow-through cell apparatus that simulates the in vivo environment, allowing for the assessment of controlled drug release over an extended period.

Answer: D. Solubility of drug is 10 times in water than octanol

Explanation: A logP of -1 indicates that the drug is more hydrophilic, meaning it is about 10 times more soluble in water than in octanol. This impacts its absorption and distribution properties.

Answer: B. caprolactam

Explanation: Nylon 6 is produced by the ring-opening polymerization of caprolactam. This process yields a polyamide with excellent mechanical properties and chemical resistance.

Answer: B. True

Explanation: True density, which is the density of the solid material excluding air, is always higher than bulk, tap, or granule densities that account for void spaces between particles.

Answer: B. Polychloroprene

Explanation: Neoprene is a synthetic rubber made by polymerizing chloroprene. Its properties, such as chemical stability and resistance to weathering, make it valuable in industrial and consumer products.

Answer: C. Reverse micelles

Explanation: Reverse micelles have a core formed by hydrophilic groups surrounded by a hydrophobic shell. This configuration allows them to solubilize water-soluble compounds in nonpolar solvents.

Answer: B. Stability

Explanation: Zeta potential measurement provides an indication of the electrostatic repulsion between particles in a colloidal dispersion. A high absolute zeta potential value suggests a stable formulation with low aggregation tendency.

Answer: B. Lyotropic

Explanation: Cholesteryl esters are thermotropic, not lyotropic.

Answer: C. Highly branched but small molecules

Explanation: Dendrimers are highly branched, monodisperse macromolecules with a tree-like structure. Their uniformity and high degree of branching make them useful in drug delivery and nanotechnology applications.

Answer: B. Turpentine oil

Explanation: Turpentine oil is known for its counter-irritant properties; it is used topically to relieve pain and inflammation by stimulating local blood flow and producing a warming sensation.

Answer: A. Volume of distribution

Explanation: The loading dose of a drug is calculated based on its volume of distribution to quickly achieve the desired plasma concentration, independent of clearance or half-life.

Answer: B. N₂

Explanation: Ethylene oxide is typically mixed with nitrogen during packaging to reduce the risk of explosive mixtures with oxygen, ensuring safe storage and transport of the sterilant.

Answer: B. Aquateric and Eudgrit

Explanation: FMC Corporation’s patented enteric coating, known as Aquateric and Eudgrit, is designed to protect drugs from the acidic environment of the stomach and ensure targeted release in the intestine.

Answer: C. Albumin-bound paclitaxel

Explanation: Abraxane is a formulation of paclitaxel bound to albumin nanoparticles, which improves drug solubility, alters distribution, and reduces the use of toxic solvents in chemotherapy.

Answer: A. Disintegration, Disaggregation, Dissolution, Dissociation

Explanation: The correct sequence in drug release begins with disintegration, followed by disaggregation, then dissolution, and finally dissociation of the drug into its molecular form for absorption.

Answer: B. Ethyl cellulose

Explanation: Ethyl cellulose is a water-insoluble derivative of cellulose used in controlled-release formulations and coatings, while methyl cellulose, HPMC, and CMC are water-soluble.