Biopharmaceutics PYQs – Set 23
Subject : Biopharmaceutics
441. When one reactant is in great excess, the reaction is:
Biopharmaceutics • Pseudo‑order reactions • GPAT 2021
442. What is the renal clearance of a substance if its plasma concentration is 10 mg and the resulting urine concentration yields clearance values?
Biopharmaceutics • Renal Clearance • GPAT 2021
443. If a basic drug is reabsorbed significantly from the kidney, which statement is correct?
Biopharmaceutics • Renal Handling of Drugs • GPAT 2021
444. Kinetically x/a(a-x) is the expression for:
Biopharmaceutics • Second‑order rate laws • GPAT 2021
445. Enhancing solubility by adding a water-miscible solvent is called:
Biopharmaceutics • Solubility Enhancement • GPAT 2021
446. In case of open model intravenous infusion, Css (steady state plasma concentration) is equal to :
Biopharmaceutics • Steady‑state infusion kinetics • GPAT 2021
447. When two brands of a drug product gives same clinical results, it is termed as :
Biopharmaceutics • Therapeutic vs. bioequivalence • GPAT 2021
448. Intracellular fluid volume (including blood cells) is approximately?
Biopharmaceutics • Total Body Water Distribution • GPAT 2021
449. The complexation of Quinine with hexyl salicylate is an example of absorption by
Biopharmaceutics • Transport mechanisms • GPAT 2021
450. Arrange the following steps in sequence of their order for production of recombinant Insulin: A. Fusion of A and B chains for disulphide bond; B. Cynogen bromide treatment to remove methionine and β-galactosidase; C. Introduction of A and B chains in the plasmid containing β-galactosidase gene; D : Synthesis of A and B chains in E. coli.
Biotechnology • Complete Subject • GPAT 2021
451. Match the following enzymes in Column I with their respective functions in Column II: (i) DNA ligase, (ii) Alkaline phosphatase, (iii) Reverse transcriptase, (iv) Polynucleotide kinase.
Biotechnology • Complete Subject • GPAT 2021
452. Formation of Okazaki fragments occurs during:
Biotechnology • DNA Replication • GPAT 2021
453. ELISA is based upon
Biotechnology • ELISA mechanisms • GPAT 2021
454. For protein detection most commonly used probe is :
Biotechnology • ELISA principles • GPAT 2021
455. Which microorganism is used for the effective synthesis of interferon?
Biotechnology • Microbial interferon production • GPAT 2021
456. During the denaturation cycle in PCR, the temperature is raised to:
Biotechnology • PCR cycle parameters • GPAT 2021
457. What are the three basic steps of conventional PCR?
Biotechnology • PCR Techniques • GPAT 2021
458. RNA molecules having intrinsic catalytic activity are called as ……………
Biotechnology • Ribozyme activity • GPAT 2021
459. What is the function of restriction endonuclease?
Biotechnology • • GPAT 2021
460. What is the function of plasmid in r-DNA technology?
Biotechnology • • GPAT 2021
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