Biopharmaceutics PYQs – Set 22
Subject : Biopharmaceutics
421. Which equation describes drug dissolution rate from a tablet?
Biopharmaceutics • Drug Dissolution • GPAT 2021
422. Higuchi model is applicable to a drug that is
Biopharmaceutics • Drug Dissolution and Release Kinetics • GPAT 2021
423. Passive diffusion follows which order of kinetics?
Biopharmaceutics • Drug Dissolution and Release Kinetics • GPAT 2021
424. The useful variable from in vitro dissolution test data for IVIVC includes
Biopharmaceutics • Drug Dissolution and Release Kinetics • GPAT 2021
425. To rule out the probability of dose dumping from an oral CR dosage form, USP includes which sampling time point where D is the normal dosing interval
Biopharmaceutics • Drug Dissolution and Release Kinetics • GPAT 2021
426. Under which of the following conditions does in‑vitro–in‑vivo correlation for a drug fail?
Biopharmaceutics • Drug Dissolution and Release Kinetics • GPAT 2021
427. The rate limiting step for the absorption of controlled release tablet is the:
Biopharmaceutics • Drug Dissolution and Release Kinetics • GPAT 2021
428. What should be the log P value for an ideal drug candidate for transdermal permeation:
Biopharmaceutics • Drug Dissolution and Release Kinetics • GPAT 2021
429. What is the typical size (in Å) of aqueous-filled pores in membranes?
Biopharmaceutics • Drug Distribution • GPAT 2021
430. Which tissue shows the least drug binding in an antivascular context?
Biopharmaceutics • Drug Distribution • GPAT 2021
431. Distribution of which drugs is perfusion‐rate limited?
Biopharmaceutics • Drug Distribution • GPAT 2021
432. p-glycoprotein (p-gp) is highly expressed on:
Biopharmaceutics • Drug Transporters & P‑gp • GPAT 2021
433. Very weak bases having pKa < 5:-
Biopharmaceutics • Drugs Acting on Autonomic Nervous System • GPAT 2021
434. Ion trapping is defined as:
Biopharmaceutics • Ion trapping • GPAT 2021
435. Which mechanism of metabolism of drug is not affected by weight change of patient ?
Biopharmaceutics • Metabolic pathways unaffected by weight • GPAT 2021
436. A concentration vs. time curve drawn from a single oral dose allows calculation of
Biopharmaceutics • Pharmacokinetic Modeling • GPAT 2021
437. For a drug (initial concentration 28 units/mL) following first‐order kinetics, the half-life is approximately:
Biopharmaceutics • Pharmacokinetics • GPAT 2021
438. Which is NOT a cause of nonlinear pharmacokinetics?
Biopharmaceutics • Pharmacokinetics • GPAT 2021
439. For drugs A (zero order), B (first order), and C (second order) with equal rate constants, which degrades 50% first?
Biopharmaceutics • Pharmacokinetics • GPAT 2021
440. The following is/are used to determine the amount of drug bound to a protein:
Biopharmaceutics • Protein binding determination • GPAT 2021
Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive
to ensure accuracy, the information may not always be up-to-date or complete. The creators are
not liable for any errors or consequences. Verify any information before relying on it for critical decisions.
इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने
का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के
लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
https://www.growuppharma.in
यदि कोई गलती है या सुझाव हो तो ईमेल करें: growuppharmacy@gmail.com