GPAT PYQs – Set 67

By Atul Sahu • GPAT PYQs

GPAT PYQs – Set 67

Year: 2019

1324. Gabriel ring closure method is employed for the synthesis of :

Organic Chemistry • Heterocyclic Chemistry

A. 1, 4-oxazine" B. Aziridine C. Oxirane D. Oxaziridine

1325. “Shake well” label must be placed on the containers of :

Pharmaceutical Technology • Ophthalmic suspensions

A. Opthalmic suspension B. Occuserts C. Opthalmic solution D. Opthalmic gels

1326. In case of Aerosol testing, valve delivering acceptance criteria for a volume of 54 mL or less

Pharmaceutical Technology • Aerosol testing

A. ± 75% B. ± 5% C. ± 10% D. ± 15%

1327. Containers may be rendered free from pyrogens by adequate cleaning and by:

Pharmaceutical Technology • Pyrogen removal

A. Autoclaving at 121°C for 15 minutes B. Heating at 210°C for 3-4 hours C. Autoclaving at 121°C for 1 hour D. Heating at 100°C for 3-4 hours

1328. GMP regulation are pertaining to minimum requirements to be met by industry when :

Pharmaceutical Jurisprudence • cGMP (21 CFR 211)

A. Manufacturing, packaging and holding of human drugs and veterinary drugs" B. Manufacture of human drugs and veterinary drugs C. Manufacture and packaging of human drugs and veterinary drugs D. Manufacture and holding of human drugs and veterinary drugs

1329. Which one of the following viscometers can be used for characterizing non-Newtonian system ?

Pharmaceutical Technology • Rheology measurement

A. Falling sphere viscometer B. Cup and Bob viscometer C. Capillary viscometer D. Hoeppler viscometer

1330. For drug substances with highly variable pharmacokinetic characteristics the following Bioequivalence study design is used

Biopharmaceutics • Bioequivalence design

A. Parallel Design B. Non-Replicate Design C. Non-Parallel Design D. Replicate Design

1331. Roll-tube technique is the modification of :

Microbiology • Anaerobe culture methods

A. Pour plate technique B. The streak-plate technique C. Micromanipulator technique D. Spread plate technique

1332. Which mechanism of metabolism of drug is not affected by weight change of patient ?

Biopharmaceutics • Metabolic pathways unaffected by weight

A. Conjugative metabolism B. Acetylation metabolism C. Hydrolytic metabolism D. Oxidative metabolism

1333. 21 CFR part 211 of USFDA describes :

Pharmaceutical Jurisprudence • US cGMP regulations

A. Current good clinical practice B. Current good packaging practice C. Current good manufacturing practice D. Current good laboratory practice

1334. In treating immunodeficiency disease the goal is to maintain IgG levels at about :

Microbiology • Immunoglobulin replacement

A. 100 mg/dL B. 400 mg/dL C. 200 mg/dL D. 300 mg/dL

1335. Which one of the following is the property of micro-emulsion ?

Pharmaceutical Technology • Microemulsion properties

A. They have particle size more than 1 micron B. They have poor stability C. They exhibit a viscoelastic gel phase, when internal phase is added in excess D. They have milky yellow colour

1336. The rheological and functional properties of synovial fluid are impaired due to :

Human Anatomy and Physiology • Synovial fluid rheology

A. Increase in the content of mucus B. Decrease in the content of mucus C. Increase in the content of hyaluronic acid D. Decrease in the content of hyaluronic acid

1337. Movement of charged particle through a liquid under the influence of an applied potential difference is known as

Physical and Inorganic Chemistry • Electrokinetic phenomena

A. Sedimentation Potential B. Streaming Potential C. Electrophoresis D. Electroosmosis

1338. As per US FDA, NDA’s for new chemical entities are classified as either :

Pharmaceutical Jurisprudence • FDA NDA review types

A. ‘P’ for product review or ‘S’ for standard review B. ‘P’ for priority review or ‘S’ for standard review C. ‘P’ for product review or ‘S’ for safety review D. ‘P’ for priority review or ‘S’ for safety review

1339. In preformulation study polymorphs can be detected by

Pharmaceutical Technology • Preformulation

A. Counter-current chromatography B. Retractometry C. High performance liquid chromatography D. Differential scanning

1340. The following is/are used to determine the amount of drug bound to a protein:

Biopharmaceutics • Protein binding determination

A. Equilibrium dialysis B. Solubility C. pH titration D. Distribution method

1341. In tablet, hydroxy propyl methyl cellulose is used as :

Pharmaceutical Technology • Tablet excipient functions

A. Diluent B. Film former C. Disintegrant D. Binder

1342. Dakin’s solution is a synonym for :

Pharmaceutical Technology • Antiseptic formulations

A. Ammonium Acetate solution B. Chlorinated soda solution C. Chloroxylenlol solution D. Aluminium Acetate solution

1343. MEDLINE, EMBASE, EBM AND IDIs are :

Pharmacology • General Pharmacology

A. Drug databases B. New compendial specification of drugs C. Chronicles of drug standards D. Source for drug patents

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

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GPAT PYQs – Set 67

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