GPAT PYQs – Set 38

Year: 2015

744. Match the drugs with the receptors that they inhibit: 1. 5HT2 agonist, 2. 5HT antagonist, 3. 5HT2 antagonist, 4. 5HT agonist

Pharmacology • autocoids

A. Options: (a) 1-S, 2-R, 3-Q, 4-P B. (b) 1-R, 2-S, 3-T, 4-P C. (c) 1-Q, 2-R, 3-T, 4-Q D. (d) 1-T, 2-Q, 3-P, 4-S

745. Passive immunity in newborn babies is due to

Microbiology • Immunology and Vaccines

A. IgG B. IgM C. IgE D. IgA

746. Upper consulate temperature and lower consulate temperature are related to

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. CMC temperature B. Kraft temperature C. Cloud temperature D. Absolute temperature

747. Which of the following molecular properties can be determined by thermogravimetric analysis?

Pharmaceutical Analysis • Spectroscopy

A. Solubility B. Hygroscopicity C. Color stability D. Hydrolysis

748. A pharmaceutical company plans to market a generic version of a drug whose patent has expireD : Which type of documentation must be submitted to the FDA?

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. IND B. NDA C. ANDA D. SNDA & Letter of intent

749. Which of the following does not produce an azeotropic mixture with water?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Methanol B. Ethanol C. Propanol D. none

750. For a particular drug, if the rate (but not the extent) of absorption is affected by food in the GIT, then taking the drug with food will result in

Biopharmaceutics • ADME

A. Smaller AUC B. Smaller Cmax C. Shorter time to reach Cmax D. Smaller fractional bioavailability and total clearance

751. According to USP, alcohol contains

Pharmaceutical Technology • Preformulation

A. 94.9–96% Ethanol B. 94.9–96% Methanol C. 50% Ethanol D. 50% Methanol

752. What does it mean that a cell is polyploid?

Human Anatomy and Physiology • Complete Subject

A. It contains more than 2 copies of one or a few chromosomes B. It contains more than 2 copies of a full set of homologous chromosomes C. It contains more than 2 copies of its sex chromosome D. It contains more than 2 copies of its autosomal chromosomes

753. Amount of dextrose in large volume infusion fluids is typically

Pharmaceutical Technology • Preformulation

A. 5% w/v B. 10% w/v C. 25% w/v D. 50% w/v

754. Which anthelmintic has immunosuppressant activity?

Pharmacology • Antimicrobial Agents

A. Piperazine B. Levamisole C. Ivermectin D. Niclosamide

755. Choose the correct statement for PEGylation:

Biopharmaceutics • ADME

A. Used to enhance in vivo half-life of small peptides and proteins B. Avoidance of reticuloendothelial clearance C. Reduction in renal clearance D. All of the above

756. Characteristics of hemorrhagic dengue fever include

Human Anatomy and Physiology • Complete Subject

A. Reduction in platelet count B. Reduction in RBC count C. Reduction in coagulation factors D. Increased RBC count

757. The unit for specific absorbance A (1%, 1 cm) is:

Pharmaceutical Analysis • Spectroscopy

A. µg/mL B. mg/L C. liter·mol⁻¹·cm⁻¹ D. dl·g⁻¹·cm⁻¹

758. Consider the reaction: A + B → C. What is the unit of the thermodynamic equilibrium constant for this reaction?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. mol/L B. L/mol C. mol²/L² D. Dimensionless

759. Which of the following drug delivery systems does not have an orifice to release the drug?

Pharmaceutical Technology • Drug Dissolution and Release Kinetics

A. Elementary Osmotic Pump B. L-OROS C. Sandwich Osmotic Pump Tablet D. Controlled Porosity Osmotic Pump Tablet

760. Sanguinarine belongs to which subgroup?

Pharmacognosy • Alkaloids

A. Morphinans B. Benzyl isoquinolines C. Phthalide isoquinolines D. Benzophenanthrenes

761. 2,3'-Didehydro-3’-deoxy thymidine is the chemical name of which antiviral agent?

Medicinal Chemistry • Antimicrobial Agents

A. Didenosine B. Zidovudine C. Stavudine D. Zalitabine

762. Tamoxifen is a nonsteroidal drug acting at steroid receptors. It produces which type of effects?

Pharmacology • Drugs Acting on Endocrine System

A. Androgen B. Antiestrogen C. Antiprogestogen D. Estrogen

763. Which enzyme is used by HIV to form DNA in the host cell?

Biochemistry • Enzymes and Coenzymes

A. Restriction endonuclease B. DNA-directed polymerase only C. Reverse transcriptase only D. Both (b) and (c)

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

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GPAT PYQs – Set 38

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