GPAT PYQs – Set 35

Year: 2016

684. Which one of the following techniques is used to determine glass transition temperature?

Pharmaceutical Technology • Preformulation

A. X-ray diffractometry B. Raman spectroscopy C. Differential scanning calorimetry D. Atomic force microscopy

685. Match the schedules with the particulars they describe: 1. Schedule T, 2. Schedule U, 3. Schedule V, 4. Schedule Y

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. (a) 1-R, 2-S, 3-Q, 4-P B. (b) 1-S, 2-Q, 3-P, 4-R C. (c) 1-+R, 2-8, 3-P, 4-Q D. (d) 1-S, 2-R, 3-P, 4-Q

686. Which of the following UV rays cause cancer?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. UVA B. UVB C. UVC D. All of the above

687. Which are the types of antibodies involved in hypersensitivity reactions?

Microbiology • Immunology and Vaccines

A. IgG and IgD B. IgG and IgM C. IgD and IgA D. IgM and IgD

688. The term used to describe unequal distribution of colour on a tablet is

Pharmaceutical Technology • Tablet

A. Chipping B. Mottling C. Lamination D. Double impress

689. Why does acetyl chloride undergo nucleophilic substitution at a faster rate than methyl acetate?

Organic Chemistry • Name Reactions

A. The ester is more sterically hindered than the acid chloride B. The chloride ion is a better leaving group than methoxide C. The acid chloride is more sterically hindered than the ester D. The methoxide ion is a better leaving group than chloride

690. The key concept of Total Quality Management (TQM) is

Hospital & Clinical Pharmacy • Hospital Drug Distribution Systems

A. Total control of all quality-related activities B. Commitment of all employees to quality improvement and team meetings C. Top management's direct involvement D. The introduction of the ISO 9000 series

691. A drug of low water solubility when given orally is absorbed up to 90% of the administered dose. The drug belongs to which class according to BCS classification?

Biopharmaceutics • Bioavailability and Bioequivalence

A. Class IV B. Class III C. Class II D. Class I

692. Which of the following is NOT a component of an evaporator?

Pharmaceutical Engineering • Heat Transfer (Evaporation, Drying)

A. Heat exchanger B. Vacuum separator C. Condenser D. Cyclone separator

693. In Parkinson’s disease, there is a predominant loss of dopaminergic neurons in

Human Anatomy and Physiology • Complete Subject

A. Substantia nigra B. Cerebellar C. Cerebral cortex D. Locus ceruleus

694. At equilibrium, receptor occupancy is related to drug concentration by

Pharmacology • General Pharmacology

A. Henderson-Hasselbalch equation B. Hill–Langmuir equation C. Lineweaver–Burk equation D. Langmuir adsorption isotherm

695. Which method is not suitable to calculate the area under the curve (AUC)?

Biopharmaceutics • ADME

A. Least square method B. Weighing and platometry C. Trapezoid rule D. Integration of curve

696. OROS is a technology developed for/as

Pharmaceutical Technology • Drug Dissolution and Release Kinetics

A. Oral release rapid onset system B. Orally rapid disintegrating tablets C. Osmotic controlled oral drug delivery system D. Transdermal drug delivery system

697. Match the events in the tablet manufacturing process with the effects observed: 1. Rapid drying of coated tablets, 2. Use of a highly viscous solution, 3. Improper feed rate from hopper, 4. Excessive compression force

Pharmaceutical Technology • Tablet

A. (a) 1-R, 2-S, 3-Q, 4-P B. (b) 1-R, 2-S, 3-P, 4-Q C. (c) 1-S, 2-R, 3-Q, 4-P D. (d) 1-R, 2-P, 3-5, 4-Q

698. Identify the starting materials A and B in the synthesis of Clomifene. Where A: 4-hydroxy-benzophenone and B: 2-diethylamino-ethyl chloride; Where A: 4-hydroxy benzaldehyde and B: 4-methoxy aniline; Where A: 4-hydroxy-benzophenone and B: 4-methoxy aniline; Where A: 4-hydroxy-benzophenone and B: benzaldehyde

Medicinal Chemistry • Name Reactions

A. A B. B C. C D. D

699. A clinical trial is being conducted with 1500 volunteers over a period of 2 years as per protocol. The trial is in which phase?

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. Phase 1 B. Phase 2 C. Phase 3 D. Phase 4

700. Which of the following drugs has not undergone a clinical trial for its use to decrease intracranial pressure?

Pharmacology • Drugs Acting on Autonomic Nervous System

A. Dideoxyinosine B. Zidovudine C. Acetazolamide D. Nicotine

701. Colloidal dispersions exhibit which type of rheology?

Physical Pharmacy • Rheology + Kinetics & Drug Stability

A. Newtonian B. Pseudoplastic C. Non‑Newtonian D. Dilatant

702. Which of the reactive oxygen species is most dangerous to cells?

Biochemistry • Enzymes and Coenzymes

A. Singlet oxygen B. Hydroxyl radical C. Superoxide D. Peroxide

703. The Gibbs Phase rule states that

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. It holds only for systems with more than one component B. It predicts that a maximum of three phases can exist in a one-component system C. It does not count phase compositions as intensive variables D. It does not count pressure and temperature as intensive variables

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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GPAT PYQs – Set 35

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