GPAT PYQs – Set 34

By Atul Sahu • GPAT PYQs

GPAT PYQs – Set 34

Year: 2016

663. To which chemical class do the vinca alkaloids belong?

Pharmacognosy • Alkaloids

A. Tropane B. Indole C. Tryptophan D. Purine

664. An antibiotic that resembles the 3’ end of a charged tRNA molecule is

Pharmacology • Antimicrobial Agents

A. Streptomycin B. Vincamycin C. Puromycin D. Tetracycline

665. If the cohesive forces between similar molecules are less than the adhesive forces between dissimilar molecules, what deviation from Raoult’s law is observed?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Positive B. Negative C. Absent D. Either positive or negative

666. Phenylalanine, a precursor of many phenolics in higher plants, is a product of which pathway?

Pharmacognosy • Introduction to Pharmacognosy

A. Shikimic acid pathway B. Malonic acid pathway C. Mevalonic acid pathway D. Methylerthritol pathway

667. Within how many days should a pharmacist dispense diluted aqueous mixtures?

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. 7 days B. 14 days C. 21 days D. 30 days

668. Which heterocyclic ring is fused to a steroidal nucleus in Danazol?

Medicinal Chemistry • Heterocyclic Chemistry

A. Thiazole B. Isoxazole C. Imidazole D. Pyrazole

669. If a drug is distributed into total body water, how many milligrams are needed to obtain an initial plasma level of 5 mg/L in a 70 kg patient?

Biopharmaceutics • ADME

A. 210 B. 150 C. 50 D. 35

670. What does “pharmacokinetic compartment” mean?

Biopharmaceutics • ADME

A. Part of the body water in the vascular system B. Total body water C. Plasma, intracellular fluid, and anatomical water compartments where the drug is absorbed D. Part of the body water in which the change in drug concentration has the same kinetics

671. The resistance to macrolide antibiotics by gram-positive organisms is developed due to

Microbiology • Complete Subject

A. Decreased uptake of antibiotics B. Synthesis of an esterase enzyme that hydrolyzes the lactone ring C. Methylation of the 50S subunit at the antibiotic binding site D. Increased metabolism of the antibiotic

672. Platinum electrode surrounded by an outer tube, in which hydrogen passes entering through a side inlet and escaping at the bottom through the test solution, is called:

Pharmaceutical Analysis • Spectroscopy

A. Silver electrode B. Calomel electrode C. Standard hydrogen electrode D. Indicator electrode

673. The most effective agent for treating psychosis would be

Pharmacology • Drugs Acting on Central Nervous System

A. Buspirone B. Sertaline C. Dextroamphetamine D. Olanzapine

674. TGA is the regulatory body of which country?

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. Europe B. Australia C. Canada D. UK

675. Which prostaglandins have a keto function at C‑9 and an α‑hydroxyl group at C‑11 in the prostanoic acid backbone?

Pharmacology • autocoids

A. PGA B. PGI C. PGE D. PGF

676. When morphine is heated at 140°C under pressure with strong HCl, it converts into

Pharmacology • Drugs Acting on Central Nervous System

A. Morphinone B. Apomorphine C. Codeine D. Oxymorphine

677. All of the following are gram-negative rods EXCEPT

Microbiology • Complete Subject

A. Clostridium B. Escherichia C. Salmonella D. Shigella

679. Bioavailability of a drug refers to

Biopharmaceutics • Bioavailability and Bioequivalence

A. The ratio of drug excreted unchanged in urine to that excreted as metabolites B. The fraction of the drug reaching the target site to produce the action C. The length of time an administered drug is available for action D. The percentage of the administered dose that reaches systemic circulation unchanged

680. Following intravenous administration, drugs are distributed fastest to

Biopharmaceutics • ADME

A. The skin, kidney, and brain B. The liver, kidney, and brain C. The liver, adipose tissue, and brain D. The liver, kidney, and adipose tissue

681. Which of the following agents acts as a hypoglycemic via ATP‑sensitive potassium channel blockade?

Pharmacology • Drugs Acting on Endocrine System

A. Mitiglinide B. Pioglitazone C. Liraglutide D. Sitagliptin

682. Identify the vibrational modes shown by sulfur dioxide molecule in IR spectroscopy:

Pharmaceutical Analysis • Spectroscopy

A. Symmetric stretching and asymmetric stretching B. Symmetric stretching and scissoring C. Asymmetric stretching and scissoring D. Symmetric stretching, asymmetric stretching, and scissoring

683. Match the drugs with their adverse effects: 1. Cyclophosphamide, 2. Doxorubicin, 3. Bleomycin, 4. Cisplatin

Pharmacology • General Pharmacology

A. (a) 1-5, 2-R, 3-P, 4-Q B. (b) 1-P, 2-Q, 3-5, 4-R C. (c) 1-P, 2-S, 3-Q, 4-R D. (d) 1-R, 2-5, 3-P, 4-Q

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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GPAT PYQs – Set 34

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