GPAT PYQs – Set 33

Year: 2016

642. Drugs (price control) order 1995 and related orders are enforced by

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. NPPA B. CSIR C. DBT D. ICMR

643. Match the drugs with the plant from which they are isolated and their families: 1. Artemisinin, 2. Diosgenin, 3. Etoposide, 4. Vinblastine and Vincristine

Pharmacognosy • Alkaloids

A. (a) 1-R-iv, 2-S-i, 3-Q-iii, 4-P-ii B. (b) 1-s-iv, 2-R-i, 3-Q-iii, 4-P-ii C. (c) 1-Q-iii, 2-R-ii, 3-Q-i, 4-P-iv D. (d) 1-R-iv, 2-S-iii, 3-Q-i, 4-P-ii

644. Which of the following is an irreversible phenomenon related to the stability of an emulsion?

Pharmaceutical Technology • Emulsion

A. Cracking B. Creaming C. Coalescence D. Flocculation

645. If a drug is highly bound to plasma proteins, what might be its consequence?

Biopharmaceutics • ADME

A. It is most likely carried by α‑glycoprotein B. It has a high renal clearance C. It has a large volume of distribution D. It is a likely candidate for drug interactions

646. In order to make a generic substitution, a pharmacist must also act as a hydrogen bond acceptor by:

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. Notifying the patient of the substitution B. Charging the same or lower price for the generic C. Placing the brand name on the label and writing “substitute for” D. Obtaining the physician’s consent to substitute the product

647. Which of the following groups can form ionic interactions and also act as a hydrogen bond acceptor?

Organic Chemistry • General Organic Chemistry

A. Hydroxyl group (OH) B. Carboxylate group (RCOO–) C. Aminonium group (RNH₃⁺) D. Ketone (C=O)

648. Which of the following drugs does not give a pink colour with ruthenium red?

Pharmacognosy • Volatile oil + Tannin + Resins

A. Agar B. Guar gum C. Pectin D. Isabgol

649. Ethyl-2 (p-chlorophenoxy)-2-methyl propionate is IUPAC name of:

Medicinal Chemistry • General Organic Chemistry

A. Fenofibrate B. Colestipol C. Clofibrate D. Colesevelam

650. Method of inspections used to determine the absorption rate constants assumes that

Biopharmaceutics • ADME

A. Ka is at least five times greater than the elimination rate B. Absorption is complete (>95%) at the time of peak concentration C. Both absorption and elimination are first order processes D. PandQ

651. The clinical trial registry in India is maintained by

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. World Health Organization, Delhi B. Indian Council of Medical Research, New Delhi C. Institute of Clinical Research, New Delhi D. Central Drugs Standard Control Organization, New Delhi

652. What is the correct order for unsaturation in the following fatty acids: 1. Palmitoleic Acid, 2. Linolenic Acid, 3. Linoleic acid, 4. Arachidonic acid

Biochemistry • Lipid and Protein Metabolism

A. 1>2>3>4 B. 3>4>2>1 C. 4>3>2>1 D. 4>2>3>1

653. Which of the following is an example of a diazonium ion?

Organic Chemistry • General Organic Chemistry

A. CH₃N⁺ B. CH₂N⁺ C. HN–NH⁺ D. None of these

654. Which term describes "the degree to which a set of inherent properties of a product system fulfills requirements"

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. Standard B. Quality C. Quality objective D. State of control

655. What will be the AUC value of lidocaine if the administered dose is 0.2 g and the total body clearance is 45 L/h?

Biopharmaceutics • Bioavailability and Bioequivalence

A. 4.44 h·mg/L B. 0.0044 h·mg/L C. 9.00 h·mg/L D. 9000 h·mg/L

656. Toluene is converted to which compound in the presence of CrO₃ and acetic anhydride?

Organic Chemistry • Name Reactions

A. Benzyl alcohol B. Benzaldehyde C. Benzoic acid D. Benzoin

657. Match the antimalarial drugs with their modes of action: 1. Artemisinin, 2. Pyremethamine, 3. Quinine, 4. Atovaquone/Proguanil

Pharmacology • Antimicrobial Agents

A. (a) 1-P, 2-S, 3-Q, 4-R B. (b) 1-Q, 2-5, 3-P, 4-R C. (c) 1-S, 2-R, 3-Q, 4-P D. (d) 1-R, 2-S, 3-Q, 4-P

658. Methyl ether of erythromycin is

Pharmacology • Antimicrobial Agents

A. Clarithromycin B. Dirithromycin C. Azithromycin D. Mithramycin

659. Ebullioscopic method is based on which observation?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Freezing point depression B. Boiling point elevation C. Osmotic pressure change D. None of the above

661. Which of the antibodies provides passive immunity to a newborn baby?

Microbiology • Immunology and Vaccines

A. IgG B. IgM C. IgA D. IgE

662. Increased number of mitoses may be present in all of the following tissues EXCEPT

Human Anatomy and Physiology • Complete Subject

A. Bone marrow cells B. Nails C. Hepatocytes D. Intestinal cells

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

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GPAT PYQs – Set 33

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