NIPER PYQs – Set 90

By Atul Sahu • NIPER PYQs

NIPER PYQs – Set 90

Year: 2020

1781. Recently ranitidine, metformin were in news due to presence of which impurity?

Pharmacology & Toxicology • Drug Safety

A. Nitrosodimethylamine B. Methylnitrile C. Diethylene glycol D. 4-aminobiphenyl

1782. Fries rearrangement reaction of phenol ester leads to the formation which type of product?

Organic Chemistry & Bulk Drugs • Reaction Mechanisms

A. Alkene B. Aldehyde C. Alcohol D. Ketone

1783. In which medium Favorskii rearrangement does occur?

Organic Chemistry & Bulk Drugs • Reaction Conditions

A. Neutral B. Acidic C. Basic D. Amhiprotic

1784. Glycine and proline are the most abundant amino acids in the structure of

Pharmaceutical Biotechnology • Protein Structure

A. Hemoglobin B. Myoglobin C. Insulin D. Collagen

1785. Which of the following is an opioid-like agonist?

Pharmacology & Toxicology • Opioids

A. Phenobarbital B. Diltiazem C. Pemoline D. Propoxyphene

1786. Which of the following compounds will not absorb UV radiations?

Pharmaceutical Analysis • Spectroscopy

A. Chloral hydrate B. Salicylic acid C. Acetanalide D. Chloramphenicol

1787. Which of the following is not aromatic?

Organic Chemistry & Bulk Drugs • Aromaticity

A. Thiophene B. Dioxane C. Pyrrole D. Isoxazole

1788. Alcohol and carboxylic acid in presence of dehydrating agent gives which compounds?

Organic Chemistry & Bulk Drugs • Esterification

A. Amides B. Esters C. β-hydroxyketone D. Anhydride

1789. Considering 'fluid mosaic model' of cell membrane, which one of the following statements is CORRECT with respect to the movement of lipids and proteins from one lipid monolayer to the other (flip-flop movement)?

Pharmaceutics & Formulation • Membrane Dynamics

A. Neither lipids, nor proteins can flip-flop B. Both lipids and proteins can flip-flop C. While lipids can rarely flip-flop, proteins can not D. While proteins can flip-flop, lipids can not

1790. How many chiral centers are present in one molecule of camphor?

Organic Chemistry & Bulk Drugs • Stereochemistry

A. 0 B. 1 C. 2 D. 3

1791. Cilostazol, a drug used in the treatment of intermittent claudication, inhibits which phosphodiesterase enzyme for its clinical effect?

Pharmacology & Toxicology • Phosphodiesterase Inhibitors

A. PDE3 B. PDE4 C. PDE5 D. PDE6

1792. Which of the following antiplatelet drugs is a reversible inhibitor of ADP receptors?

Pharmacology & Toxicology • Antiplatelet Agents

A. Clopidogrel B. Prasugrel C. Ticagrelor D. All of the above

1793. The most essential fatty acid is

Pharmaceutical Biotechnology • Fatty Acids

A. Linolenic acid B. Oleic acid C. Arachidonic acid D. Palmitic acid

1794. Carbonyl group can be reduced to alkane with the help of catalyst

Organic Chemistry & Bulk Drugs • Reduction Reactions

A. H2N-NH2, KOH, heat B. Zn/Hg HCl C. LiAlH4 D. P, Q and R

1795. When the velocity of enzyme activity is plotted against substrate concentration, which of the following is obtained?

Pharmaceutical Biotechnology • Enzyme Kinetics

A. Parabola B. Hyperbolic Curve C. Straight line with positive slope D. Straight line with negative slope

1796. The active site of chymotrypsin consists of a catalytic triad of which of the following amino acid residues?

Pharmaceutical Biotechnology • Enzyme Structure

A. Serine, histidine and glutamate B. Threonine, histidine and aspartate C. Serine, histidine and aspartate D. Methionine, histidine and aspartate

1797. Which of the following types of lipid aggregates has maximum stability?

Pharmaceutics & Formulation • Lipid Aggregates

A. Micelles B. Bilayer C. Liposome D. Myelin sheath

1798. Which of the following is choline containing lipid?

Natural Products • Lipids

A. Phosphatidylserine B. Phosphatidylglycerol C. Phosphatidylethanolamine D. Sphingomyelin

1799. Volhard's method of chloride ion determination

Pharmaceutical Analysis • Titrimetric Methods

A. is back titration with ammonium thioscyanat B. is direct titration with ammonium thioscyanate C. uses dichlorofluorescein as indicator D. uses potassium chromate

1800. Which of the following is an ergot derivative?

Natural Products • Alkaloids

A. Bergapten B. Bretylium C. Bupropion D. Bromocriptine

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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NIPER PYQs – Set 90

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