GPAT PYQs – Set 21
Year: 2018
401. Materials whose consistency depends on both the duration of shear and the rate of shear exhibit:-
Physical Pharmacy • Rheology + Kinetics & Drug Stability
402. Which of the following solutions are more likely to have the same osmotic pressure?
Physical and Inorganic Chemistry • Acids, Bases, and Buffers
403. Which statements are correct for micelle formation? (P) Micelles are dynamic structures that are continually formed and broken down in solution; (Q) The typical micelle diameter is about 2–3 μm; (R) Micelle formation is a spontaneous process; (S) When the surfactant concentration is increased above the CMC, the number of micelles increases and the free surfactant concentration decreases below CMC.
Physical and Inorganic Chemistry • Surface and Interfacial Tension
404. Which equation is used to predict the stability of a drug product at room temperature from experiments at accelerated temperature?
Pharmaceutical Engineering • Heat Transfer (Evaporation, Drying)
405. Which statement correctly describes Hess’ Law?
Physical and Inorganic Chemistry • Physical and Inorganic Chemistry
406. Which of the following is an aryl acetic acid derivative:
Medicinal Chemistry • General Organic Chemistry
407. The role of glutathione in tissues includes all except:-
Biochemistry • Enzymes and Coenzymes
408. When Ke is constant and Ka is larger, the pharmacokinetic effect is:-
Biopharmaceutics • ADME
409. When considering drug delivery to the brain, which of the following is false?
Biopharmaceutics • ADME
410. IVIVC utilizes the principles of statistical moment analysis, corresponding to which level?
Biopharmaceutics • Bioavailability and Bioequivalence
411. The systems that follow the Weibull Mathematical Model used to describe drug release kinetics include:
Pharmaceutical Engineering • Controlled‑Release Technologies
412. Which method is used by pharmacists for complete blending of potent powders with large quantities of diluents?
Hospital & Clinical Pharmacy • Compounding and Incompatibilities
413. Substance used to reduce friction during tablet compression and facilitate ejection from the die cavity is called:-
Pharmaceutical Technology • Tablet
414. What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?
Pharmaceutical Technology • Formulation Calculations
415. The proportion of NaCl liquid to give a 1.5% solution of drug isotonic with blood plasma is:- (Given: Freezing point of 1% w/v drug solution is -0.122 °C and of NaCl is -0.576 °C)
Biopharmaceutics • Bioavailability and Bioequivalence
416. Which of the following statements is NOT TRUE about prokaryotes?
Microbiology • Complete Subject
417. Match the following diseases with their causative organisms. Column I: Creutzfeldt-Jakob disease, Typhus, Syphilis, Plague; Column II: Yersinia pestis, Prions, Rickettsia prowazekii, Treponema pallidum.
Microbiology • Immunology and Vaccines
418. As the dielectric constant increases, the polarity of the solvents:
Physical and Inorganic Chemistry • Physical and Inorganic Chemistry
419. The angle of repose is calculated by:
Physical Pharmacy • States of Matter + Micromeritics + Surface and Interfacial Tension
420. Spray drying/spray congealing method is generally used to prepare:-
Pharmaceutical Engineering • Microcapsules
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