GPAT PYQs – Set 15

By Atul Sahu • GPAT PYQs

GPAT PYQs – Set 15

Year: 2023

281. Which molecular characteristic enhances aqueous solubility of a solute?

Biopharmaceutics • Bioavailability and Bioequivalence

A. A high melting point B. The presence of a polar group C. A high molecular surface area D. A high boiling point

282. Which in-vitro/in-vivo correlation level compares % drug released to % drug absorbed?

Biopharmaceutics • Bioavailability and Bioequivalence

A. Level C B. Level A C. Multiple Level C D. Level B

283. Which characteristic is most associated with a high apparent volume of distribution?

Biopharmaceutics • ADME

A. Penetration across blood–brain and blood–testis barriers B. Extensive plasma protein binding C. Distribution into total body water D. Extensive tissue binding

284. Ostwald's dilution law is applicable to

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Weak electrolytes B. Strong electrolytes C. Non-electrolytes D. All electrolytes

285. Which of the following is not typically used as an NSAID?

Pharmacology • autocoids

A. Indomethacin extended release 75 mg B. Aspirin 75 mg C. Naproxen 500 mg D. Mefenamic acid 500 mg

286. Autoimmunity refers to

Microbiology • Immunology and Vaccines

A. An automatic trigger of the immune system against specific pathogens B. Failure to distinguish between self and non-self C. An automatic segregation of T and B cells D. Failure of B-cells to interact with T-cells

287. Bioavailability studies are ideally carried out in which group of volunteers?

Biopharmaceutics • Bioavailability and Bioequivalence

A. Aged individuals B. Children C. Healthy individuals D. Patients

288. Which of the following is acellular?

Microbiology • Complete Subject

A. Bacteria B. Fungus C. Virus D. Amoeba

289. Given two statements about Salicylic Acid Ointment and Wool Alcohol Ointment, which is correct?

Pharmaceutical Technology • Semisolid + Suppository + Aerosol

A. Both statements are true and Reason explains Assertion B. Both statements are true but Reason does not explain Assertion C. Assertion is true but Reason is false D. Assertion is false but Reason is true

290. Replacement of the diazonium group by halogen in the presence of copper powder is called

Organic Chemistry • Name Reactions

A. Transfection B. Transduction C. Conjugation D. Transformation

291. In a mechanical model of a viscoelastic material with elements in series, the model is termed as

Physical Pharmacy • Rheology + Kinetics & Drug Stability

A. Voigt Element B. Creep Element C. Maxwell Element D. Retardation Element

292. Which equation explains the increase in solubility with decreasing particle size?

Pharmaceutical Technology • Preformulation

A. Log(S0/S)=2γMr/2.303RTρ B. Log(S/S0)=2γMr/2.303RTρ C. Log(S0/S)=2γMr/2.303 RTρr D. Log(S/S0)=2γM/2.303 RTρr

293. Match List I with List II for dissolution apparatus: A. Type 1, B. Type 5, C. USP App 6, D : USP App 7; and List II: I. Reciprocating holder, II. Paddled overdisk, III. Basket type, IV. Cylinder apparatus.

Pharmaceutical Technology • Preformulation

A. (A)-(III); (B)-(II); (C)-(IV); (D)-(I) B. (A)-(IV); (B)-(I); (C)-(II); (D)-(III) C. (A)-(II); (B)-(III); (C)-(I); (D)-(II) D. (A)-(I); (B)-(II); (C)-(III); (D)-(IV)

294. A clear, sweetened hydroalcoholic liquid containing medicament is known as

Pharmaceutical Technology • Preformulation

A. Elixir B. Syrup C. Tincture D. Decoction

295. The Schick test is used to determine susceptibility to

Microbiology • Immunology and Vaccines

A. Measles B. Diptheria C. Polio D. Typhoid

296. Absorption of Vitamin B12 is facilitated by

Human Anatomy and Physiology • Complete Subject

A. Hydrogel B. Glycoprotein C. Lipoprotein D. Mucoprotein

297. A sample of glucose decomposed at 140°C in 0.030 M HCl had a rate constant of 0.0080 hr⁻¹, with a spontaneous rate of 0.0010 hr⁻¹. The catalytic coefficient kH is

Physical and Inorganic Chemistry • Rheology + Kinetics & Drug Stability

A. 0.22 per mole per hour B. 0.233 per mole per hour C. 0.27 per mole per hour D. 0.29 per mole per hour

298. Match List I with List II for emulsifiers: A. Triethanolamine oleate, B. N‑ethyl N‑ethy morpholinium ethosulfate, C. Polyoxyethylene sorbitan monooleate, D : Gelatin; and List II: I. Surface-active agent (non-ionic), II. Hydrophilic colloid, III. Surface-active agent (anionic), IV. w/o Emulsifier (HLB=4.3).

Physical Pharmacy • Formulation of Lipsticks, Creams, and Lotions

A. (A)-(II); (B)-(IV); (C)-(V); (D)-(III) B. (A)-(III); (B)-(V); (C)-(I); (D)-(II) C. (A)-(V); (B)-(IV); (C)-(II); (D)-(III) D. (A)-(IV); (B)-(III); (C)-(V); (D)-(I)

299. Which equipment is based on the principle of Pohlman liquid whistle?

Pharmaceutical Engineering • Mixing and Size Reduction

A. Ultrasonifier B. Mechanical stirrer C. Silverson homogeniser D. Colloid mill

300. Which of the following is the correct sequence for particle size measurement techniques? (a) Sieve, (b) Anderson Pipette, (c) Coulter counter, (d) Light scattering

Pharmaceutical Engineering • Size Reduction and Mixing

A. a. b. c, d B. b, d, c, a C. a, c, b, d D. d, a, c, b

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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GPAT PYQs – Set 15

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