GPAT PYQs – Set 14

By Atul Sahu • GPAT PYQs

GPAT PYQs – Set 14

Year: 2023

261. ___ is an example of an aromatic nucleophilic substitution reaction.

Organic Chemistry • Name Reactions

A. Chichibabin B. Gatterman Koch reaction C. Kolbes reaction D. Friedel-Crafts reaction

262. Amphetamine undergoes metabolic conversion to 1-phenyl-2-propanol via which reaction?

Pharmacology • Drugs Acting on Central Nervous System

A. Hydrolysis B. Oxidation C. Reduction D. Hydroxylation

263. What is the popular common name for (m-hydroxyphenyl)-trimethyl ammonium methyl sulphate dimethyl carbamate?

Pharmacology • Drugs Acting on Autonomic Nervous System

A. Neostigmine B. Pyridostigmine C. Physostigmine D. Metastigmine

264. Which of the following compounds absorbs at the longest wavelength

Pharmaceutical Analysis • Spectroscopy

A. 1,3,5‑Hexatriene B. 1,3,5,7‑Octatetraene C. 1,7‑Diphenyl‑1,3,5‑heptatriene D. 1,6‑Diphenyl‑1,3,5‑heptatriene

265. Which cephalosporin contains an unusual 5-thio-1,2,3,4-tetrazole substituent attached via a methylene bridge?

Pharmacology • Antimicrobial Agents

A. Cefazolin B. Cefamandole C. Cefoxitin D. Cefadroxil

266. Which of the following molecules has a net dipole moment?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. CS2 B. CHCl3 C. CH4 D. CO2

267. The Michaelis‑Menten hypothesis

Pharmaceutical Analysis • Spectroscopy

A. Postulates the formation of an enzyme‑substrate complex B. Enables calculation of an enzyme’s isoelectric point C. States that the reaction rate may be independent of substrate concentration D. States that the reaction rate is proportional to substrate concentration

268. Which one of the following is an example of a chelate?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Cisplatin B. Hemoglobin C. Iodine D. Ferrocene

269. A 2.0% saline solution is considered

Pharmaceutical Technology • Preformulation

A. Hypotonic B. Hypertonic C. Isotonic D. Iso-osmotic

270. The C-2 epimer of D-glucose is

Biochemistry • Carbohydrate Metabolism

A. D-Mannose B. L-Fructose C. D-Gluco pyranose D. L-Arabinose

271. Which factor affects the heat of reaction according to Kirchhoff's equation?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Molecularity B. Temperature C. Pressure D. Volume

272. What is the correct order of stability for free radicals?

Organic Chemistry • General Organic Chemistry

A. 3° > 2° > 1° > CH3° > allyl B. 3° > 2° > 1° > allyl > CH3° C. CH3° > 3° > 2° > 1° > allyl D. allyl > 3° > 2° > 1° > CH3°

273. Which statement regarding voltage-sensitive calcium channels is correct?

Pharmacology • Drugs Acting on Cardiovascular System

A. L-type Blocker: Nifedipine B. T-type Blocker: Verapamil C. N-type Blocker: Mibefradil D. R-type Blocker: Diltiazem

274. Hixon Crowell’s cube root law of dissolution states that

Pharmaceutical Analysis • Spectroscopy

A. There is a change in particle size and surface area during dissolution B. The dissolution process is controlled by diffusion of molecules/ions C. High free energy of activation is required for dissolution D. Renewal of the surface fluid layer around the drug particle

275. EDTA is an example of which type of ligand?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Unidentate Ligand B. Bidentate Ligand C. Tridentate Ligand D. Hexadentate Ligand

276. Isoquinoline treated with oleum at 90°C yields predominantly which product?

Organic Chemistry • Heterocyclic Chemistry

A. Isoquinoline-3-sulfonic acid B. Isoquinoline-5-sulfonic acid C. Isoquinoline-6-sulfonic acid D. Isoquinoline-7-sulfonic acid

277. Eicosanoids are derived from polyunsaturated fatty acids containing how many carbons?

Biochemistry • Lipid and Protein Metabolism

A. 30 B. 25 C. 15 D. 20

278. Efficiency of a reversible engine is determined by which theorem?

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Clapeyron equation B. Claussius Clapeyron equation C. Gibbs-Helmholtz equation D. Carnot theorem

279. Noye-Whitney's equation predicts that

Pharmaceutical Technology • Preformulation

A. an increase in dissolution rate occurs with reduced particle size due to increased surface area B. a relationship between diffusion coefficient and molecular size C. the influence of electrolyte concentration on dissolution rate D. an equilibrium between surfactant molecules at interfaces

280. One of the following drugs is not intended for systemic use

Pharmacology • Antimicrobial Agents

A. Netilmycin B. Sisomicin C. Neomycin D. Paramomycin

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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GPAT PYQs – Set 14

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