GPAT PYQs – Set 10

By Atul Sahu • GPAT PYQs

GPAT PYQs – Set 10

Year: 2023

181. Clathrates crystallize in the form of:

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Channel‑type structure B. Tetragonal‑type structure C. Cubic‑type lattice D. Cage‑like lattice

182. Which of the following ointment bases is an absorption base?

Pharmaceutical Technology • Semisolid + Suppository + Aerosol

A. Yellow ointment, USP B. Hydrophilic petrolatum, USP C. Hydrophilic ointment, USP D. PEG ointment, NF

183. Which of the following drugs has an apparent volume of distribution of approximately 6500 liters?

Biopharmaceutics • ADME

A. Amoxicillin B. Ibuprofen C. Chloroquine D. Diazepam

184. Which of the following surfactants is an anionic surfactant?

Pharmaceutical Technology • Emulsion

A. Lecithin B. Sorbitan esters C. Benzalkonium chloride D. Soaps

185. Match the following concept in List I with parameters in List II: A. Volume of Distribution B. Evans Blue C. 3.5–5% D : Metallothionin. Choose the correct matching.

Biopharmaceutics • Bioavailability and Bioequivalence

A. A–I, B–II, C–III, D–IV B. A–V, B–IV, C–III, D–II C. A–IV, B–I, C–II, D–V D. A–III, B–II, C–IV, D–V

186. Basic dyes are used in microbiological staining. Which statement is wrong about the mechanism of staining?

Microbiology • Complete Subject

A. Positive ions on the bacterial surface form a colored complex with the dye B. Ionic exchange occurs between negative bacterial charge and positive dye charge C. Ionic exchange occurs between positive bacterial charge and negative dye charge D. Neutral bacterial charge forms a colored complex with the basic dye

187. Which term describes the partial or complete separation of the top or body crowns of a tablet from the main body of the tablet?

Pharmaceutical Technology • Tablet

A. Lamination B. Capping C. Picking D. Mottling

188. Which of the following formulations are pharmaceutically equivalent?

Pharmaceutical Technology • Tablet

A. A and B B. B and C C. A and C D. B and D

189. What is the approximate amount of powder (in mg) that can be filled in empty gelatin capsules of size 00?

Pharmaceutical Technology • Capsule

A. 1040 mg B. 650 mg C. 325 mg D. 162 mg

190. The interfacial forces are related to the contact angle by:

Physical Pharmacy • States of Matter + Micromeritics + Surface and Interfacial Tension

A. Nernst equation B. Stokes equation C. Young’s equation D. Laplace equation

191. In the Langmuir isotherm, which statement is true except one: the layer of the gas adsorbed is one molecule thick, adsorbed layer is uniform, no desorption occurs upon collision, and no interaction occurs between adjacent molecules. Identify the exception.

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. The layer is one molecule thick B. Adsorbed layer is uniform C. No desorption takes place when gas strikes the solid surface D. No interaction between adjacent adsorbed molecules

192. In the absence of prescriber instruction, the dose given for a mixture preparation should be stated on the label as:

Hospital & Clinical Pharmacy • Hospital Drug Distribution Systems

A. One 5‑mL spoonful three times a day B. Two 5‑mL spoonfuls three times a day C. Two 5‑mL spoonfuls twice a day D. One 5‑mL spoonful twice a day

193. Suspensions containing a high percentage (about 50% or greater) of small, deflocculated particles would show which flow property?

Physical Pharmacy • Rheology + Kinetics & Drug Stability

A. Plastic flow B. Dilatant flow C. Newtonian flow D. Pseudoplastic flow

194. Which one is the right sequence of the intermediates in the biosynthesis of opium alkaloids: A. Tyrosine B. Reticuline C. Codeine D : Morphine E. Thebaine?

Pharmacognosy • Alkaloids

A. A, B, C, D, E B. A, B, E, C, D C. A, B, E, D, C D. A, B, D, E, C

195. Arrange the following intermediates in the synthesis of isoprenoids in the right sequence: A. Squalene B. Farnesyl PP C. Geranyl PP D : Acetyl CoA E. Mevalonate.

Biochemistry • Carbohydrate Metabolism

A. D, B, C, A, E B. D, E, C, B, A C. B, C, D, A, E D. E, B, C, A, D

196. If resins contain benzoic acids or cinnamic acids, they are called:

Pharmacognosy • Volatile oil + Tannin + Resins

A. Colophony B. Balsams C. Glucoresins D. Resene

197. Lycopodium spores are used in quantitative microscopy for the following: determining % purity of drugs, estimating foreign organic matter, measuring single‑layered tissue area, etc. Identify the correct uses:

Pharmacognosy • Introduction to Pharmacognosy

A. A, B, and C only B. A, B, and D only C. A only D. B and D only

198. The ring structure present in strychnine alkaloid is:

Pharmacognosy • Alkaloids

A. Indole B. Purine C. Phenanthrene D. Imidazole

199. Isabgol belongs to the family:

Pharmacognosy • Introduction to Pharmacognosy

A. Apocynaceae B. Plantaginaceae C. Solanaceae D. Golaceae

200. Lignin is a complex polymer that can be stained pink in tissue using which chemicals?

Pharmacognosy • Introduction to Pharmacognosy

A. Chloral hydrate and phloroglucinol B. Chlor‑zinc‑iodine C. Phloroglucinol and hydrochloric acid D. Chloral hydrate, zinc, and ammonia

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GPAT PYQs – Set 10

GPAT PYQs – Set 10

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GPAT PYQs – Set 10

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