GPAT PYQs – Set 1

Year: 2024

1. The key intermediate for the biosynthesis of C6-C3 units is:

Pharmacognosy • Introduction to Pharmacognosy

A. Pyruvic acid B. Dehydroquinic acid C. Shikimic acid D. Mevalonic acid

2. According to the SAR of Chloroquine electron:

Pharmacology • Antimicrobial Agents

A. Donating group at 6th position of the quinoline ring is important for the inhibition of hemozoin formation B. Withdrawing group at 6th position of the quinoline ring is important for the inhibition of hemozoin formation C. Donating group at 7th position of the quinoline ring is important for the inhibition of hemozoin formation D. Withdrawing group at 7th position of the quinoline ring is important for the inhibition of hemozoin formation

3. Coating of Eudragit NE40D on tablets is done to prepare:

Pharmaceutical Technology • Tablet

A. Buccal tablets B. Sublingual tablets C. CR tablets D. IR tablets

4. The dried juice of Pterocarpus marsupium belongs to the family:

Pharmacognosy • Introduction to Pharmacognosy

A. Rosaceae B. Asteraceae C. Liliaceae D. Leguminosae

5. Examples of BCS class III drugs are:

Biopharmaceutics • Bioavailability and Bioequivalence

A. Taxol, Ellagic acid, Aspirin B. Chloroquine, Diltiazem, Metoprolol C. Acyclovir, Atenolol, Captopril D. Aspirin, Paracetamol, Amoxycillin

6. Chikusetsu saponin is present in:

Pharmacognosy • Glycosides

A. Senega B. Ginseng C. Quillia D. Liquorice

7. Schedule T of Drugs and Cosmetics Rules, 1945 deals with:

Pharmaceutical Jurisprudence • Drugs and Cosmetics Act, 1940

A. GMP for Homeopathy medicine B. GMP for ASU drugs C. GLP and requirement of premises and equipments D. GMP for Pharmaceutical product

8. Which one of the following enzymes comprises a major part of enzyme-linked receptors:

Pharmacology • General Pharmacology

A. Receptor Serine Phosphatase B. Receptor Tyrosine Kinase C. Receptor Histidine Kinase D. Receptor Threonine Phosphatase

9. Spin Quantum number of 13C NMR is:

Physical and Inorganic Chemistry • Physical and Inorganic Chemistry

A. Tue Apr 01 2025 12:30:00 GMT+0530 (India Standard Time) B. Mon Feb 03 2025 13:30:00 GMT+0530 (India Standard Time) C. Sat Mar 01 2025 13:30:00 GMT+0530 (India Standard Time) D. Sat Feb 01 2025 13:30:00 GMT+0530 (India Standard Time)

10. During compression of tablets, dwell time is:

Pharmaceutical Technology • Tablet

A. Time it takes for the punches to eject tablet under the primary compression rollers B. Time it takes for the punches to eject the tablets C. Time it takes for the punches to stop moving vertically and to achieve maximum penetration in the die under the primary compression rollers D. Time it takes for the punches to punch tablet

11. Arrange the following steps in sequence of their order for production of recombinant Insulin: A. Fusion of A and B chains for disulphide bond; B. Cynogen bromide treatment to remove methionine and β-galactosidase; C. Introduction of A and B chains in the plasmid containing β-galactosidase gene; D : Synthesis of A and B chains in E. coli.

Biotechnology • Complete Subject

A. a→b→d→c B. d→c→a→b C. c→d→b→a D. b→a→d→c

12. The Wilson's disease is a rare inherited disorder due to accumulation in brain, liver and other vital organs of:

Pharmacology • autocoids

A. Iodine B. Calcium C. Iron D. Copper

13. Which of the following is a meta directing group:

Organic Chemistry • General Organic Chemistry

A. NHCH3 B. CF3 C. F D. NH2

14. Chromatographic techniques such as gas chromatography and liquid chromatography are not appropriate for separation of amino acids because

Pharmaceutical Analysis • Chromatography

A. Amino acids are high polarity substances B. Amino acids are low polarity substances C. Amino acids are non polar substances D. Amino acids have low charge

15. Which of the following is not a method for solubility enhancement:

Pharmaceutical Technology • Preformulation

A. Crystallization B. Co-solvency C. Hydrotropy D. Salt formation

16. The bloom strength is directly proportional to:

Pharmaceutical Technology • Rheology + Kinetics & Drug Stability

A. Density B. Viscosity C. Measure of the strength and stiffness of the gelatin D. Molecular weight

17. Match the following enzymes in Column I with their respective functions in Column II: (i) DNA ligase, (ii) Alkaline phosphatase, (iii) Reverse transcriptase, (iv) Polynucleotide kinase.

Biotechnology • Complete Subject

A. (a) i–r, ii–s, iii–p, iv–q B. (b) i–p, ii–q, iii–r, iv–s C. (c) i–q, ii–r, iii–p, iv–s D. (d) i–s, ii–p, iii–q, iv–r

18. What is the best time to collect the medicinal bark material:

Pharmacognosy • Introduction to Pharmacognosy

A. After the leaf falls B. Post flowering C. Pre flowering D. Before the leaf falls

19. Which antibiotic undergoes light catalysed autoxidation:

Pharmacology • Antimicrobial Agents

A. Sugar derived antibiotics B. Polyene antibiotics C. Macrolide antibiotics D. Beta lactum antibiotics

20. Size of a pilot plant batch is:

Pharmaceutical Engineering • Heat Transfer (Evaporation, Drying)

A. 1/10th of marketing batch B. 1/5th of marketing batch C. 1/5th of production batch D. 1/10th of production batch

Disclaimer for MCQ Quiz
The questions in this MCQ quiz are intended solely for educational purposes. While we strive to ensure accuracy, the information may not always be up-to-date or complete. The creators are not liable for any errors or consequences. Verify any information before relying on it for critical decisions.

इस MCQ क्विज़ के प्रश्न केवल शैक्षिक उद्देश्यों के लिए हैं। हम सामग्री की सटीकता सुनिश्चित करने का प्रयास करते हैं, फिर भी जानकारी हमेशा अद्यतित या पूर्ण नहीं हो सकती। निर्माता किसी भी परिणाम के लिए जिम्मेदार नहीं हैं। कृपया किसी भी महत्वपूर्ण निर्णय से पहले स्वतंत्र रूप से जांचें।
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GPAT PYQs – Set 1

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